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Tissue Inhibitor of Metalloprotease-2 (TIMP-2): Bioprocess Development, Physicochemical, Biochemical, and Biological Characterization of Highly Expressed Recombinant Protein

Tissue inhibitor of metalloprotease-2 (TIMP-2) is a secreted 21 kDa multifunctional protein first described as an endogenous inhibitor of matrix metalloproteinases (MMPs) that prevents breakdown of the extracellular matrix often observed in chronic diseases. TIMP-2 diminishes the level of growth fac...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Chowdhury, Anandã, Brinson, Robert, Wei, Beiyang, Stetler-Stevenson, William G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322544/
https://ncbi.nlm.nih.gov/pubmed/29140689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00700
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