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Paternal Exposure to Cyclophosphamide Affects the Progression of Sperm Chromatin Decondensation and Activates a DNA Damage Response in the Prepronuclear Rat Zygote(1)
Spermatozoon decondensation in the zygote leads to the initiation of chromatin remodeling during which protamines are removed and replaced with maternal histones. We hypothesize that damage to male germ cells induced by paternal exposure to cyclophosphamide may alter the timing of spermatozoal decon...
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| Izdano u: | Biol Reprod |
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| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6322429/ https://ncbi.nlm.nih.gov/pubmed/20393171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.109.083345 |
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