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Epigenetic programming in the preimplantation rat embryo is disrupted by chronic paternal cyclophosphamide exposure
Preconceptional paternal exposure to cyclophosphamide, a widely used anticancer agent, leads to increases in embryo loss, malformations, and behavioral deficits in offspring; these abnormalities are transmissible to subsequent generations [Auroux, M., Dulioust, E., Selva, J. & Rince, P. (1990) M...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1138259/ https://ncbi.nlm.nih.gov/pubmed/15911775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501200102 |
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