Human-like NSG mouse glycoproteins sialylation pattern changes the phenotype of human lymphocytes and sensitivity to HIV-1 infection

BACKGROUND: The use of immunodeficient mice transplanted with human hematopoietic stem cells is an accepted approach to study human-specific infectious diseases such as HIV-1 and to investigate multiple aspects of human immune system development. However, mouse and human are different in sialylation...

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Detalhes bibliográficos
Publicado no:BMC Immunol
Main Authors: Dagur, Raghubendra Singh, Branch-Woods, Amanda, Mathews, Saumi, Joshi, Poonam S., Quadros, Rolen M., Harms, Donald W., Cheng, Yan, Miles, Shana M., Pirruccello, Samuel J., Gurumurthy, Channabasavaiah B., Gorantla, Santhi, Poluektova, Larisa Y.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322283/
https://ncbi.nlm.nih.gov/pubmed/30616506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-018-0279-3
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