Determining the Mutation Bias of Favipiravir in Influenza Virus Using Next-Generation Sequencing

Favipiravir is a broad-spectrum antiviral drug that may be used to treat influenza. Previous research has identified that favipiravir likely acts as a mutagen, but the precise mutation bias that favipiravir induces in influenza virus RNAs has not been described. Here, we use next-generation sequenci...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Goldhill, Daniel H., Langat, Pinky, Xie, Hongyao, Galiano, Monica, Miah, Shahjahan, Kellam, Paul, Zambon, Maria, Lackenby, Angie, Barclay, Wendy S.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2019
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321902/
https://ncbi.nlm.nih.gov/pubmed/30381482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01217-18
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