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The mechanism of resistance to favipiravir in influenza

Favipiravir is a broad-spectrum antiviral that has shown promise in treatment of influenza virus infections. While emergence of resistance has been observed for many antiinfluenza drugs, to date, clinical trials and laboratory studies of favipiravir have not yielded resistant viruses. Here we show e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Goldhill, Daniel H., te Velthuis, Aartjan J. W., Fletcher, Robert A., Langat, Pinky, Zambon, Maria, Lackenby, Angie, Barclay, Wendy S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233120/
https://ncbi.nlm.nih.gov/pubmed/30352857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1811345115
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