Favipiravir-resistant influenza A virus shows potential for transmission

Favipiravir is a nucleoside analogue which has been licensed to treat influenza in the event of a new pandemic. We previously described a favipiravir resistant influenza A virus generated by in vitro passage in presence of drug with two mutations: K229R in PB1, which conferred resistance at a cost t...

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Pubblicato in:PLoS Pathog
Autori principali: Goldhill, Daniel H., Yan, Ada, Frise, Rebecca, Zhou, Jie, Shelley, Jennifer, Gallego Cortés, Ana, Miah, Shahjahan, Akinbami, Omolola, Galiano, Monica, Zambon, Maria, Lackenby, Angie, Barclay, Wendy S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8195362/
https://ncbi.nlm.nih.gov/pubmed/34061908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008937
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