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The mechanism of resistance to favipiravir in influenza

Favipiravir is a broad-spectrum antiviral that has shown promise in treatment of influenza virus infections. While emergence of resistance has been observed for many antiinfluenza drugs, to date, clinical trials and laboratory studies of favipiravir have not yielded resistant viruses. Here we show e...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Goldhill, Daniel H., te Velthuis, Aartjan J. W., Fletcher, Robert A., Langat, Pinky, Zambon, Maria, Lackenby, Angie, Barclay, Wendy S.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233120/
https://ncbi.nlm.nih.gov/pubmed/30352857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1811345115
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