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Direct Single-Molecule Observation of Sequential DNA Bending Transitions by the Sox2 HMG Box
Sox2 is a pioneer transcription factor that initiates cell fate reprogramming through locus-specific differential regulation. Mechanistically, it was assumed that Sox2 achieves its regulatory diversity via heterodimerization with partner transcription factors. Here, utilizing single-molecule fluores...
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| Udgivet i: | Int J Mol Sci |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6321608/ https://ncbi.nlm.nih.gov/pubmed/30518054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19123865 |
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