Class I Phosphoinositide 3-Kinase PIK3CA/p110α and PIK3CB/p110β Isoforms in Endometrial Cancer

The phosphoinositide 3-kinase (PI3K) signalling pathway is highly dysregulated in cancer, leading to elevated PI3K signalling and altered cellular processes that contribute to tumour development. The pathway is normally orchestrated by class I PI3K enzymes and negatively regulated by the phosphatase...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Mazloumi Gavgani, Fatemeh, Smith Arnesen, Victoria, Jacobsen, Rhîan G., Krakstad, Camilla, Hoivik, Erling A., Lewis, Aurélia E.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321576/
https://ncbi.nlm.nih.gov/pubmed/30544563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19123931
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