PIK3CB/p110β is a selective survival factor for glioblastoma

BACKGROUND: Glioblastoma (GBM) is difficult to treat. Phosphoinositide 3-kinase (PI3K) is an attractive therapeutic target for GBM; however, targeting this pathway to effectively treat GBM is not successful because the roles of PI3K isoforms remain to be defined. The aim of this study is to determin...

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Vydáno v:Neuro Oncol
Hlavní autoři: Pridham, Kevin J, Le, Lamvy, Guo, Sujuan, Varghese, Robin T, Algino, Sarah, Liang, Yanping, Fajardin, Renee, Rodgers, Cara M, Simonds, Gary R, Kelly, Deborah F, Sheng, Zhi
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909664/
https://ncbi.nlm.nih.gov/pubmed/29016844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox181
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