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Insight into Inhibitor Binding in the Eukaryotic Proteasome: Computations of the 20S CP

A combination of molecular dynamics (MD) simulations and computational analyses uncovers structural features that may influence substrate passage and exposure to the active sites within the proteolytic chamber of the 20S proteasome core particle (CP). MD simulations of the CP reveal relaxation dynam...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Mol Sci
Egile Nagusiak: Hodošček, Milan, Elghobashi-Meinhardt, Nadia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321098/
https://ncbi.nlm.nih.gov/pubmed/30514002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19123858
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