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Simulations of NPC1(NTD):NPC2 Protein Complex Reveal Cholesterol Transfer Pathways
The Niemann Pick type C (NPC) proteins, NPC1 and NPC2, are involved in the lysosomal storage disease, NPC disease. The formation of a NPC1–NPC2 protein–protein complex is believed to be necessary for the transfer of cholesterol and lipids out of the late endosomal (LE)/lysosomal (Lys) compartments....
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| 出版年: | Int J Mol Sci |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6163316/ https://ncbi.nlm.nih.gov/pubmed/30181526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19092623 |
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