Enhanced In Vitro Antitumor Activity of GnRH-III-Daunorubicin Bioconjugates Influenced by Sequence Modification

Receptors for gonadotropin releasing hormone (GnRH) are highly expressed in various human cancers including breast, ovarian, endometrial, prostate and colorectal cancer. Ligands like human GnRH-I or the sea lamprey analogue GnRH-III represent a promising approach for the development of efficient dru...

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Bibliografiska uppgifter
I publikationen:Pharmaceutics
Huvudupphovsmän: Schuster, Sabine, Biri-Kovács, Beáta, Szeder, Bálint, Buday, László, Gardi, János, Szabó, Zsuzsanna, Halmos, Gábor, Mező, Gábor
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320914/
https://ncbi.nlm.nih.gov/pubmed/30423956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10040223
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