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Enhanced In Vitro Antitumor Activity of GnRH-III-Daunorubicin Bioconjugates Influenced by Sequence Modification

Receptors for gonadotropin releasing hormone (GnRH) are highly expressed in various human cancers including breast, ovarian, endometrial, prostate and colorectal cancer. Ligands like human GnRH-I or the sea lamprey analogue GnRH-III represent a promising approach for the development of efficient dru...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Schuster, Sabine, Biri-Kovács, Beáta, Szeder, Bálint, Buday, László, Gardi, János, Szabó, Zsuzsanna, Halmos, Gábor, Mező, Gábor
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320914/
https://ncbi.nlm.nih.gov/pubmed/30423956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10040223
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