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Comparative cell biological study of in vitro antitumor and antimetastatic activity on melanoma cells of GnRH-III-containing conjugates modified with short-chain fatty acids

Background: Peptide hormone-based targeted tumor therapy is an approved strategy to selectively block the tumor growth and spreading. The gonadotropin-releasing hormone receptors (GnRH-R) overexpressed on different tumors (e.g., melanoma) could be utilized for drug-targeting by application of a GnRH...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Lajkó, Eszter, Spring, Sarah, Hegedüs, Rózsa, Biri-Kovács, Beáta, Ingebrandt, Sven, Mező, Gábor, Kőhidai, László
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178282/
https://ncbi.nlm.nih.gov/pubmed/30344773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.14.226
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