Neutrophil cytoplasts induce Th17 differentiation and skew inflammation toward neutrophilia in severe asthma

Severe asthma is a debilitating and treatment refractory disease. As many as half of these patients have complex neutrophil predominant lung inflammation that is distinct from milder asthma with type 2 eosinophilic inflammation. New insights into severe asthma pathogenesis are needed. Here, concomit...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Immunol
Main Authors: Krishnamoorthy, Nandini, Douda, David N., Brüggemann, Thayse R., Ricklefs, Isabell, Duvall, Melody G., Abdulnour, Raja-Elie E., Martinod, Kimberly, Tavares, Luciana, Wang, Xiao, Cernadas, Manuela, Israel, Elliot, Mauger, David T., Bleecker, Eugene R., Castro, Mario, Erzurum, Serpil C., Gaston, Benjamin M., Jarjour, Nizar N., Wenzel, Sally, Dunican, Eleanor, Fahy, John V., Irimia, Daniel, Wagner, Denisa D., Levy, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320225/
https://ncbi.nlm.nih.gov/pubmed/30076281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aao4747
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados