ALX receptor ligands define a biochemical endotype for severe asthma

BACKGROUND. In health, inflammation resolution is an active process governed by specialized proresolving mediators and receptors. ALX/FPR2 receptors (ALX) are targeted by both proresolving and proinflammatory ligands for opposing signaling events, suggesting pivotal roles for ALX in the fate of infl...

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Publicado en:JCI Insight
Autores principales: Ricklefs, Isabell, Barkas, Ioanna, Duvall, Melody G., Cernadas, Manuela, Grossman, Nicole L., Israel, Elliot, Bleecker, Eugene R., Castro, Mario, Erzurum, Serpil C., Fahy, John V., Gaston, Benjamin M., Denlinger, Loren C., Mauger, David T., Wenzel, Sally E., Comhair, Suzy A., Coverstone, Andrea M., Fajt, Merritt L., Hastie, Annette T., Johansson, Mats W., Peters, Michael C., Phillips, Brenda R., Levy, Bruce D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2017
Materias:
Clinical Medicine
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518567/
https://ncbi.nlm.nih.gov/pubmed/28724795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93534
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