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ALX receptor ligands define a biochemical endotype for severe asthma

BACKGROUND. In health, inflammation resolution is an active process governed by specialized proresolving mediators and receptors. ALX/FPR2 receptors (ALX) are targeted by both proresolving and proinflammatory ligands for opposing signaling events, suggesting pivotal roles for ALX in the fate of infl...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Ricklefs, Isabell, Barkas, Ioanna, Duvall, Melody G., Cernadas, Manuela, Grossman, Nicole L., Israel, Elliot, Bleecker, Eugene R., Castro, Mario, Erzurum, Serpil C., Fahy, John V., Gaston, Benjamin M., Denlinger, Loren C., Mauger, David T., Wenzel, Sally E., Comhair, Suzy A., Coverstone, Andrea M., Fajt, Merritt L., Hastie, Annette T., Johansson, Mats W., Peters, Michael C., Phillips, Brenda R., Levy, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518567/
https://ncbi.nlm.nih.gov/pubmed/28724795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93534
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