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Arginine metabolic endotypes in pulmonary arterial hypertension

Abstract. Decreased synthesis of nitric oxide (NO) by NO synthases (NOS) is believed to play an important role in the pathogenesis of pulmonary arterial hypertension (PAH). Multiple factors may contribute to decreased NO bioavailability, including increased activity of arginase, the enzyme that conv...

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Detalhes bibliográficos
Publicado no:Pulm Circ
Main Authors: Kao, Christina C., Wedes, Samuel H., Hsu, Jean W., Bohren, Kurt M., Comhair, Suzy A. A., Jahoor, Farook, Erzurum, Serpil C.
Formato: Artigo
Idioma:Inglês
Publicado em: University of Chicago Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405713/
https://ncbi.nlm.nih.gov/pubmed/25992277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/679720
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