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Arginine metabolic endotypes in pulmonary arterial hypertension

Abstract. Decreased synthesis of nitric oxide (NO) by NO synthases (NOS) is believed to play an important role in the pathogenesis of pulmonary arterial hypertension (PAH). Multiple factors may contribute to decreased NO bioavailability, including increased activity of arginase, the enzyme that conv...

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Detalles Bibliográficos
Publicado en:Pulm Circ
Main Authors: Kao, Christina C., Wedes, Samuel H., Hsu, Jean W., Bohren, Kurt M., Comhair, Suzy A. A., Jahoor, Farook, Erzurum, Serpil C.
Formato: Artigo
Idioma:Inglês
Publicado: University of Chicago Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405713/
https://ncbi.nlm.nih.gov/pubmed/25992277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/679720
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