Arginine metabolic endotypes in pulmonary arterial hypertension

Abstract. Decreased synthesis of nitric oxide (NO) by NO synthases (NOS) is believed to play an important role in the pathogenesis of pulmonary arterial hypertension (PAH). Multiple factors may contribute to decreased NO bioavailability, including increased activity of arginase, the enzyme that conv...

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Enregistré dans:
Détails bibliographiques
Publié dans:Pulm Circ
Auteurs principaux: Kao, Christina C., Wedes, Samuel H., Hsu, Jean W., Bohren, Kurt M., Comhair, Suzy A. A., Jahoor, Farook, Erzurum, Serpil C.
Format: Artigo
Langue:Inglês
Publié: University of Chicago Press 2015
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405713/
https://ncbi.nlm.nih.gov/pubmed/25992277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/679720
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