Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers

We report the detection of endometrial and ovarian cancers based on genetic analyses of DNA recovered from the fluids obtained during a routine Papanicolaou (Pap) test. The new test, called PapSEEK, incorporates assays for mutations in 18 genes as well as an assay for aneuploidy. In Pap brush sample...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Wang, Yuxuan, Li, Lu, Douville, Christopher, Cohen, Joshua D., Yen, Ting-Tai, Kinde, Isaac, Sundfelt, Karin, Kjær, Susanne K., Hruban, Ralph H., Shih, Ie-Ming, Wang, Tian-Li, Kurman, Robert J., Springer, Simeon, Ptak, Janine, Popoli, Maria, Schaefer, Joy, Silliman, Natalie, Dobbyn, Lisa, Tanner, Edward J., Angarita, Ana, Lycke, Maria, Jochumsen, Kirsten, Afsari, Bahman, Danilova, Ludmila, Levine, Douglas A., Jardon, Kris, Zeng, Xing, Arseneau, Jocelyne, Fu, Lili, Diaz, Luis A., Karchin, Rachel, Tomasetti, Cristian, Kinzler, Kenneth W., Vogelstein, Bert, Fader, Amanda N., Gilbert, Lucy, Papadopoulos, Nickolas
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320220/
https://ncbi.nlm.nih.gov/pubmed/29563323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aap8793
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