In Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse Model

Synthetically engineered DNA-encoded monoclonal antibodies (DMAbs) are an in vivo platform for evaluation and delivery of human mAb to control against infectious disease. Here, we engineer DMAbs encoding potent anti-Zaire ebolavirus (EBOV) glycoprotein (GP) mAbs isolated from Ebola virus disease sur...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Patel, Ami, Park, Daniel H., Davis, Carl W., Smith, Trevor R.F., Leung, Anders, Tierney, Kevin, Bryan, Aubrey, Davidson, Edgar, Yu, Xiaoying, Racine, Trina, Reed, Charles, Gorman, Marguerite E., Wise, Megan C., Elliott, Sarah T.C., Esquivel, Rianne, Yan, Jian, Chen, Jing, Muthumani, Kar, Doranz, Benjamin J., Saphire, Erica Ollmann, Crowe, James E., Broderick, Kate E., Kobinger, Gary P., He, Shihua, Qiu, Xiangguo, Kobasa, Darwyn, Humeau, Laurent, Sardesai, Niranjan Y., Ahmed, Rafi, Weiner, David B.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319964/
https://ncbi.nlm.nih.gov/pubmed/30428362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.062
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker