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Suppression, disaggregation, and modulation of γ‐Synuclein fibrillation pathway by green tea polyphenol EGCG

Oligomerization of γ‐Synuclein is known to have implications for both neurodegeneration and cancer. Although it is known to co‐exist with the fibrillar deposits of α‐Synuclein (Lewy bodies), a hallmark in Parkinson's disease (PD), the effect of potential therapeutic modulators on the fibrillati...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Roy, Sneha, Bhat, Rajiv
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319761/
https://ncbi.nlm.nih.gov/pubmed/30394624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3549
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