Green tea polyphenol EGCG blunts androgen receptor function in prostate cancer

Androgen deprivation therapy is the major treatment for advanced prostate cancer (PCa). However, it is a temporary remission, and the patients almost inevitably develop hormone refractory prostate cancer (HRPC). HRPC is almost incurable, although most HRPC cells still express androgen receptor (AR)...

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Hlavní autoři: Siddiqui, Imtiaz A., Asim, Mohammad, Hafeez, Bilal B., Adhami, Vaqar M., Tarapore, Rohinton S., Mukhtar, Hasan
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2011
Témata:
Research Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058706/
https://ncbi.nlm.nih.gov/pubmed/21177307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-167924
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