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Suppression, disaggregation, and modulation of γ‐Synuclein fibrillation pathway by green tea polyphenol EGCG

Oligomerization of γ‐Synuclein is known to have implications for both neurodegeneration and cancer. Although it is known to co‐exist with the fibrillar deposits of α‐Synuclein (Lewy bodies), a hallmark in Parkinson's disease (PD), the effect of potential therapeutic modulators on the fibrillati...

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Dettagli Bibliografici
Pubblicato in:Protein Sci
Autori principali: Roy, Sneha, Bhat, Rajiv
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319761/
https://ncbi.nlm.nih.gov/pubmed/30394624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3549
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