Continuous and bolus intraventricular topotecan prolong survival in a mouse model of leptomeningeal medulloblastoma

Leptomeningeal metastasis remains a difficult clinical challenge. Some success has been achieved by direct administration of therapeutics into the cerebrospinal fluid (CSF) circumventing limitations imposed by the blood brain barrier. Here we investigated continuous infusion versus bolus injection o...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Shackleford, Gregory M., Mahdi, Min Y., Moats, Rex A., Hawes, Debra, Tran, Hung C., Finlay, Jonathan L., Hoang, Tuan Q., Meng, Ellis F., Erdreich-Epstein, Anat
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2019
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319703/
https://ncbi.nlm.nih.gov/pubmed/30608927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206394
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak