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Transglutaminase 2 Promotes Autophagy by LC3 Induction through p53 Depletion in Cancer Cell
Transglutaminase 2 (TGase 2) plays a key role in p53 regulation, depleting p53 tumor suppressor through autophagy in renal cell carcinoma. We found that microtubule-associated protein 1A/1B-light chain 3 (LC3), a hallmark of autophagy, were tightly associated with the level of TGase 2 in cancer cell...
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| Publicado no: | Biomol Ther (Seoul) |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Korean Society of Applied Pharmacology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6319544/ https://ncbi.nlm.nih.gov/pubmed/30231606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2018.140 |
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