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Matriptase cleaves the amyloid-beta peptide 1–42 at Arg-5, Lys-16, and Lys-28

OBJECTIVE: The type-II transmembrane extracellular serine protease matriptase was shown to cleave at Arg-102 in the amino-terminal region of the amyloid precursor protein (APP). In this study we determined matriptase cleavage sites in the amyloid-beta (Aβ) peptide region of APP (Asp-597 to Ala-638 i...

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Publicado en:BMC Res Notes
Main Authors: Chen, Li-Mei, Chai, Karl X.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318999/
https://ncbi.nlm.nih.gov/pubmed/30606244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-018-4040-z
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