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DBS: a fast and informative segmentation algorithm for DNA copy number analysis

BACKGROUND: Genome-wide DNA copy number changes are the hallmark events in the initiation and progression of cancers. Quantitative analysis of somatic copy number alterations (CNAs) has broad applications in cancer research. With the increasing capacity of high-throughput sequencing technologies, fa...

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Détails bibliographiques
Publié dans:BMC Bioinformatics
Auteurs principaux: Ruan, Jun, Liu, Zhen, Sun, Ming, Wang, Yue, Yue, Junqiu, Yu, Guoqiang
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318921/
https://ncbi.nlm.nih.gov/pubmed/30606105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2565-8
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