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DBS: a fast and informative segmentation algorithm for DNA copy number analysis

BACKGROUND: Genome-wide DNA copy number changes are the hallmark events in the initiation and progression of cancers. Quantitative analysis of somatic copy number alterations (CNAs) has broad applications in cancer research. With the increasing capacity of high-throughput sequencing technologies, fa...

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Pubblicato in:BMC Bioinformatics
Autori principali: Ruan, Jun, Liu, Zhen, Sun, Ming, Wang, Yue, Yue, Junqiu, Yu, Guoqiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318921/
https://ncbi.nlm.nih.gov/pubmed/30606105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2565-8
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