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DBS: a fast and informative segmentation algorithm for DNA copy number analysis

Abstract Background Genome-wide DNA copy number changes are the hallmark events in the initiation and progression of cancers. Quantitative analysis of somatic copy number alterations (CNAs) has broad applications in cancer research. With the increasing capacity of high-throughput sequencing technolo...

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Detalhes bibliográficos
Main Authors: Jun Ruan, Zhen Liu, Ming Sun, Yue Wang, Junqiu Yue, Guoqiang Yu
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-01-01
Colecção:BMC Bioinformatics
Acesso em linha:http://link.springer.com/article/10.1186/s12859-018-2565-8
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