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Reconstructing DNA copy number by joint segmentation of multiple sequences
BACKGROUND: Variations in DNA copy number carry information on the modalities of genome evolution and mis-regulation of DNA replication in cancer cells. Their study can help localize tumor suppressor genes, distinguish different populations of cancerous cells, and identify genomic variations respons...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3534631/ https://ncbi.nlm.nih.gov/pubmed/22897923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-205 |
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