Identification of therapeutic targets in chordoma through comprehensive genomic and transcriptomic analyses

Chordoma is a rare, orphan cancer arising from embryonal precursors of bone. Surgery and radiotherapy (RT) provide excellent local control, often at the price of significant morbidity because of the structures involved and the need for relatively high doses of RT; however, recurrence remains high. A...

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Veröffentlicht in:Cold Spring Harb Mol Case Stud
Hauptverfasser: Liang, Winnie S., Dardis, Christopher, Helland, Adrienne, Sekar, Shobana, Adkins, Jonathan, Cuyugan, Lori, Enriquez, Daniel, Byron, Sara, Little, Andrew S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2018
Schlagworte:
Research Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318766/
https://ncbi.nlm.nih.gov/pubmed/30322893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a003418
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