Alzheimer’s disease is associated with altered expression of genes involved in immune response and mitochondrial processes in astrocytes

Alzheimer’s disease (AD) is characterized by deficits in cerebral metabolic rates of glucose in the posterior cingulate (PC) and precuneus in AD subjects, and in APOEε4 carriers, decades prior to the onset of measureable cognitive deficits. However, the cellular and molecular basis of this phenotype...

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Détails bibliographiques
Publié dans:Neurobiol Aging
Auteurs principaux: Sekar, Shobana, McDonald, Jacquelyn, Cuyugan, Lori, Aldrich, Jessica, Kurdoglu, Ahmet, Adkins, Jonathan, Serrano, Geidy, Beach, Thomas G., Craig, David W., Valla, Jonathan, Reiman, Eric M., Liang, Winnie S.
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315763/
https://ncbi.nlm.nih.gov/pubmed/25448601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.09.027
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