Circular RNA expression and regulatory network prediction in posterior cingulate astrocytes in elderly subjects

Abstract Background Circular RNAs (circRNAs) are a novel class of endogenous, non-coding RNAs that form covalently closed continuous loops and that are both highly conserved and abundant in the mammalian brain. A role for circRNAs in sponging microRNAs (miRNAs) has been proposed, but the circRNA-miR...

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Hauptverfasser: Shobana Sekar, Lori Cuyugan, Jonathan Adkins, Philipp Geiger, Winnie S. Liang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2018-05-01
Schriftenreihe:BMC Genomics
Schlagworte:
Circular RNAs
Astrocytes
Posterior cingulate
Aging
Regulatory network
Online Zugang:http://link.springer.com/article/10.1186/s12864-018-4670-5
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