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Isoalantolactone suppresses LPS-induced inflammation by inhibiting TRAF6 ubiquitination and alleviates acute lung injury

Isoalantolactone (IAL) is a sesquiterpene lactone extracted from roots of Inula helenium L and has shown anti-inflammatory effects. In this study we investigated the therapeutic effects of IAL on acute lung injury (ALI) and elucidated the mechanisms underlying its anti-inflammation potential in vitr...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Ding, Yun-he, Song, Yun-duan, Wu, Ya-xian, He, Hui-qiong, Yu, Tian-hong, Hu, Yu-dong, Zhang, De-peng, Jiang, Hong-chao, Yu, Kai-kai, Li, Xiao-zong, Sun, Lei, Qian, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318348/
https://ncbi.nlm.nih.gov/pubmed/30013035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0061-3
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