Initial Protein Unfolding Events in Ubiquitin, Cytochrome c and Myoglobin Are Revealed with the Use of 213 nm UVPD Coupled to IM-MS

The initial stages of protein unfolding may reflect the stability of the entire fold and can also reveal which parts of a protein can be perturbed, without restructuring the rest. In this work, we couple UVPD with activated ion mobility mass spectrometry to measure how three model proteins start to...

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Bibliografiske detaljer
Udgivet i:J Am Soc Mass Spectrom
Main Authors: Theisen, Alina, Black, Rachelle, Corinti, Davide, Brown, Jeffery M., Bellina, Bruno, Barran, Perdita E.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2018
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Focus: Honoring Carol V. Robinson's Election to the National Academy of Sciences: Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318241/
https://ncbi.nlm.nih.gov/pubmed/29949061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-018-1992-0
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