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Initial Protein Unfolding Events in Ubiquitin, Cytochrome c and Myoglobin Are Revealed with the Use of 213 nm UVPD Coupled to IM-MS

The initial stages of protein unfolding may reflect the stability of the entire fold and can also reveal which parts of a protein can be perturbed, without restructuring the rest. In this work, we couple UVPD with activated ion mobility mass spectrometry to measure how three model proteins start to...

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Detalhes bibliográficos
Publicado no:J Am Soc Mass Spectrom
Main Authors: Theisen, Alina, Black, Rachelle, Corinti, Davide, Brown, Jeffery M., Bellina, Bruno, Barran, Perdita E.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318241/
https://ncbi.nlm.nih.gov/pubmed/29949061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-018-1992-0
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