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Simplified Identification of Disulfide, Trisulfide, and Thioether Pairs with 213 nm UVPD
Disulfide heterogeneity and other non-native crosslinks introduced during therapeutic antibody production and storage could have considerable negative effects on clinical efficacy, but tracking these modifications remains challenging. Analysis must also be carried out cautiously to avoid introductio...
Gardado en:
| Publicado en: | Analyst |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6197924/ https://ncbi.nlm.nih.gov/pubmed/30264084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8an01582a |
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