PRKRA/PACT Expression Promotes Chemoresistance of Mucinous Ovarian Cancer

For mucinous ovarian cancer (MOC), standard platinum based therapy is largely ineffective. We sought to identify possible mechanisms of oxaliplatin resistance of MOC and develop strategies to overcome this resistance. A kinome-based small interfering RNA (siRNA) library screen was carried out using...

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Veröffentlicht in:Mol Cancer Ther
Hauptverfasser: Hisamatsu, Takeshi, McGuire, Michael, Wu, Sherry Y., Rupaimoole, Rajesha, Pradeep, Sunila, Bayraktar, Emine, Noh, Kyunghee, Hu, Wei, Hansen, Jean M., Lyons, Yasmin, Gharpure, Kshipra M., Nagaraja, Archana S., Mangala, Lingegowda S., Mitamura, Takashi, Rodriguez-Aguayo, Cristian, Eun, Young Gyu, Rose, Johnathon, Bartholomeusz, Geoffrey A, Ivan, Cristina, Lee, Ju-Seog, Matsuo, Koji, Frumovitz, Michael, Wong, Kwong K., Lopez-Berestein, Gabriel, Sood, Anil K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318044/
https://ncbi.nlm.nih.gov/pubmed/30305341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-1050
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