PRKRA/PACT Expression Promotes Chemoresistance of Mucinous Ovarian Cancer

For mucinous ovarian cancer (MOC), standard platinum based therapy is largely ineffective. We sought to identify possible mechanisms of oxaliplatin resistance of MOC and develop strategies to overcome this resistance. A kinome-based small interfering RNA (siRNA) library screen was carried out using...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Hisamatsu, Takeshi, McGuire, Michael, Wu, Sherry Y., Rupaimoole, Rajesha, Pradeep, Sunila, Bayraktar, Emine, Noh, Kyunghee, Hu, Wei, Hansen, Jean M., Lyons, Yasmin, Gharpure, Kshipra M., Nagaraja, Archana S., Mangala, Lingegowda S., Mitamura, Takashi, Rodriguez-Aguayo, Cristian, Eun, Young Gyu, Rose, Johnathon, Bartholomeusz, Geoffrey A, Ivan, Cristina, Lee, Ju-Seog, Matsuo, Koji, Frumovitz, Michael, Wong, Kwong K., Lopez-Berestein, Gabriel, Sood, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318044/
https://ncbi.nlm.nih.gov/pubmed/30305341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-1050
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