PRKRA/PACT Expression Promotes Chemoresistance of Mucinous Ovarian Cancer

For mucinous ovarian cancer (MOC), standard platinum based therapy is largely ineffective. We sought to identify possible mechanisms of oxaliplatin resistance of MOC and develop strategies to overcome this resistance. A kinome-based small interfering RNA (siRNA) library screen was carried out using...

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Vydáno v:Mol Cancer Ther
Hlavní autoři: Hisamatsu, Takeshi, McGuire, Michael, Wu, Sherry Y., Rupaimoole, Rajesha, Pradeep, Sunila, Bayraktar, Emine, Noh, Kyunghee, Hu, Wei, Hansen, Jean M., Lyons, Yasmin, Gharpure, Kshipra M., Nagaraja, Archana S., Mangala, Lingegowda S., Mitamura, Takashi, Rodriguez-Aguayo, Cristian, Eun, Young Gyu, Rose, Johnathon, Bartholomeusz, Geoffrey A, Ivan, Cristina, Lee, Ju-Seog, Matsuo, Koji, Frumovitz, Michael, Wong, Kwong K., Lopez-Berestein, Gabriel, Sood, Anil K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318044/
https://ncbi.nlm.nih.gov/pubmed/30305341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-1050
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