Tumor penetrating peptides inhibiting MYC as a potent targeted therapeutic strategy for triple-negative breast cancers

Overexpression of MYC oncogene is highly prevalent in many malignancies such as aggressive triple-negative breast cancers (TNBCs) and it is associated with very poor outcome. Despite decades of research, attempts to effectively inhibit MYC, particularly with small molecules, still remain challenging...

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Foilsithe in:Oncogene
Main Authors: Wang, Edina, Sorolla, Anabel, Cunningham, Paula T., Bogdawa, Heique M., Beck, Samuel, Golden, Emily, Dewhurst, Robert E., Florez, Laura, Cruickshank, Mark N., Hoffmann, Katrin, Hopkins, Richard M., Kim, Jonghwan, Woo, Andrew J., Watt, Paul M., Blancafort, Pilar
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2018
Ábhair:
Brief Communication
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318000/
https://ncbi.nlm.nih.gov/pubmed/30076412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0421-y
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