Tumor penetrating peptides inhibiting MYC as a potent targeted therapeutic strategy for triple-negative breast cancers

Overexpression of MYC oncogene is highly prevalent in many malignancies such as aggressive triple-negative breast cancers (TNBCs) and it is associated with very poor outcome. Despite decades of research, attempts to effectively inhibit MYC, particularly with small molecules, still remain challenging...

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Dettagli Bibliografici
Pubblicato in:Oncogene
Autori principali: Wang, Edina, Sorolla, Anabel, Cunningham, Paula T., Bogdawa, Heique M., Beck, Samuel, Golden, Emily, Dewhurst, Robert E., Florez, Laura, Cruickshank, Mark N., Hoffmann, Katrin, Hopkins, Richard M., Kim, Jonghwan, Woo, Andrew J., Watt, Paul M., Blancafort, Pilar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
Soggetti:
Brief Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318000/
https://ncbi.nlm.nih.gov/pubmed/30076412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0421-y
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