Tumor penetrating peptides inhibiting MYC as a potent targeted therapeutic strategy for triple-negative breast cancers

Overexpression of MYC oncogene is highly prevalent in many malignancies such as aggressive triple-negative breast cancers (TNBCs) and it is associated with very poor outcome. Despite decades of research, attempts to effectively inhibit MYC, particularly with small molecules, still remain challenging...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Wang, Edina, Sorolla, Anabel, Cunningham, Paula T., Bogdawa, Heique M., Beck, Samuel, Golden, Emily, Dewhurst, Robert E., Florez, Laura, Cruickshank, Mark N., Hoffmann, Katrin, Hopkins, Richard M., Kim, Jonghwan, Woo, Andrew J., Watt, Paul M., Blancafort, Pilar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318000/
https://ncbi.nlm.nih.gov/pubmed/30076412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0421-y
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