Tumor penetrating peptides inhibiting MYC as a potent targeted therapeutic strategy for triple-negative breast cancers

Overexpression of MYC oncogene is highly prevalent in many malignancies such as aggressive triple-negative breast cancers (TNBCs) and it is associated with very poor outcome. Despite decades of research, attempts to effectively inhibit MYC, particularly with small molecules, still remain challenging...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Oncogene
المؤلفون الرئيسيون: Wang, Edina, Sorolla, Anabel, Cunningham, Paula T., Bogdawa, Heique M., Beck, Samuel, Golden, Emily, Dewhurst, Robert E., Florez, Laura, Cruickshank, Mark N., Hoffmann, Katrin, Hopkins, Richard M., Kim, Jonghwan, Woo, Andrew J., Watt, Paul M., Blancafort, Pilar
التنسيق: Artigo
اللغة:Inglês
منشور في: Nature Publishing Group UK 2018
الموضوعات:
Brief Communication
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318000/
https://ncbi.nlm.nih.gov/pubmed/30076412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0421-y
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