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Precision medicine by designer interference peptides: applications in oncology and molecular therapeutics

In molecular cancer therapeutics only 10% of known cancer gene products are targetable with current pharmacological agents. Major oncogenic drivers, such as MYC and KRAS proteins are frequently highly overexpressed or mutated in multiple human malignancies. However, despite their key role in oncogen...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Oncogene
Hauptverfasser: Sorolla, Anabel, Wang, Edina, Golden, Emily, Duffy, Ciara, Henriques, Sónia T., Redfern, Andrew D., Blancafort, Pilar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002299/
https://ncbi.nlm.nih.gov/pubmed/31636382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-1056-3
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