Conophylline suppresses pancreatic cancer desmoplasia and cancer‐promoting cytokines produced by cancer‐associated fibroblasts

Despite recent advances in cancer treatment, pancreatic cancer is a highly malignant tumor type with a dismal prognosis and it is characterized by dense desmoplasia in the cancer tissue. Cancer‐associated fibroblasts (CAF) are responsible for this fibrotic stroma and promote cancer progression. We p...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Ishii, Norihiro, Araki, Kenichiro, Yokobori, Takehiko, Hagiwara, Kei, Gantumur, Dorgormaa, Yamanaka, Takahiro, Handa, Tadashi, Tsukagoshi, Mariko, Igarashi, Takamichi, Watanabe, Akira, Kubo, Norio, Harimoto, Norifumi, Masamune, Atsushi, Umezawa, Kazuo, Kuwano, Hiroyuki, Shirabe, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317962/
https://ncbi.nlm.nih.gov/pubmed/30353606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13847
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