Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection

Shigella spp. are pathogenic bacteria that cause bacillary dysentery in humans by invading the colonic and rectal mucosa where they induce dramatic inflammation. Here, we have analyzed the role of the soluble PRR Pentraxin 3 (PTX3), a key component of the humoral arm of innate immunity. Mice that ha...

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Dades bibliogràfiques
Publicat a:PLoS Pathog
Autors principals: Ciancarella, Valeria, Lembo-Fazio, Luigi, Paciello, Ida, Bruno, Anna-Karin, Jaillon, Sébastien, Berardi, Sara, Barbagallo, Marialuisa, Meron-Sudai, Shiri, Cohen, Dani, Molinaro, Antonio, Rossi, Giacomo, Garlanda, Cecilia, Bernardini, Maria Lina
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317801/
https://ncbi.nlm.nih.gov/pubmed/30532257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007469
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