Intracellular Shigella remodels its LPS to dampen the innate immune recognition and evade inflammasome activation

LPS is a potent bacterial effector triggering the activation of the innate immune system following binding with the complex CD14, myeloid differentiation protein 2, and Toll-like receptor 4. The LPS of the enteropathogen Shigella flexneri is a hexa-acylated isoform possessing an optimal inflammatory...

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Detalhes bibliográficos
Main Authors: Paciello, Ida, Silipo, Alba, Lembo-Fazio, Luigi, Curcurù, Laura, Zumsteg, Anna, Noël, Gaëlle, Ciancarella, Valeria, Sturiale, Luisa, Molinaro, Antonio, Bernardini, Maria Lina
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832022/
https://ncbi.nlm.nih.gov/pubmed/24167293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303641110
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