Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection

Shigella spp. are pathogenic bacteria that cause bacillary dysentery in humans by invading the colonic and rectal mucosa where they induce dramatic inflammation. Here, we have analyzed the role of the soluble PRR Pentraxin 3 (PTX3), a key component of the humoral arm of innate immunity. Mice that ha...

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發表在:PLoS Pathog
Main Authors: Ciancarella, Valeria, Lembo-Fazio, Luigi, Paciello, Ida, Bruno, Anna-Karin, Jaillon, Sébastien, Berardi, Sara, Barbagallo, Marialuisa, Meron-Sudai, Shiri, Cohen, Dani, Molinaro, Antonio, Rossi, Giacomo, Garlanda, Cecilia, Bernardini, Maria Lina
格式: Artigo
語言:Inglês
出版: Public Library of Science 2018
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317801/
https://ncbi.nlm.nih.gov/pubmed/30532257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007469
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