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DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Diabetic cardiomyopathy (DCM) is a form of idiopathic heart disease, with signs including hypertrophy of myocardial cells, hypertension-independent fibrosis and coronary artery disease. Considering the involvement of dimethylarginine dimethylaminohydrolase 2 (DDAH2) in diabetes, it was hypothesized...

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Bibliografiske detaljer
Udgivet i:Int J Mol Med
Main Authors: Zhu, Zhen-Dong, Ye, Ji-Ming, Fu, Xue-Mei, Wang, Xue-Chang, Ye, Ji-Yun, Wu, Xin-Ran, Hua, Peng, Liao, Yu-Qiong, Xuan, Wei, Duan, Jin-Lan, Li, Wei-Yuan, Fu, Hui, Xia, Zhong-Hua, Zhang, Xuan
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317674/
https://ncbi.nlm.nih.gov/pubmed/30569164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.4034
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