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Targeting the Recently Deorphanized Receptor GPR83 for the Treatment of Immunological, Neuroendocrine and Neuropsychiatric Disorders

G-protein coupled receptors (GPCRs) are a superfamily of receptors responsible for initiation of a myriad of intracellular signaling cascades. Currently, GPCRs represent approximately 34% of marketed pharmaceuticals, a large portion of which have no known endogenous ligand. These orphan GPCRs repres...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Prog Mol Biol Transl Sci
Prif Awduron: Lueptow, Lindsay M., Devi, Lakshmi A., Fakira, Amanda K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317364/
https://ncbi.nlm.nih.gov/pubmed/30340784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.pmbts.2018.07.002
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