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Targeting the Recently Deorphanized Receptor GPR83 for the Treatment of Immunological, Neuroendocrine and Neuropsychiatric Disorders
G-protein coupled receptors (GPCRs) are a superfamily of receptors responsible for initiation of a myriad of intracellular signaling cascades. Currently, GPCRs represent approximately 34% of marketed pharmaceuticals, a large portion of which have no known endogenous ligand. These orphan GPCRs repres...
Tallennettuna:
| Julkaisussa: | Prog Mol Biol Transl Sci |
|---|---|
| Päätekijät: | , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6317364/ https://ncbi.nlm.nih.gov/pubmed/30340784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.pmbts.2018.07.002 |
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